SR8185
SR8185 is a potent and selective TBK1/IKKi dual inhibitor with IC50s of 3 nM and [1].
Product Specifications
CAS Number
[1356225-62-1]
UNSPSC
12352005
Target
IKK
Related Pathways
NF-κB
Field of Research
Cancer
Smiles
O=C(N1CCCC1)NC2=CC=CC(NC3=NC=CC(C4=CC=C(N5CCCC5)C(C#N)=C4)=N3)=C2
Molecular Formula
C26H27N7O
Molecular Weight
453.54
References & Citations
[1]Li J, et al. Selective TBK1/IKKi dual inhibitors with anticancer potency. Int J Cancer. 2014 Apr 15;134 (8) :1972-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TBK1
Curated Selection
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