Tilivapram
Tilivapram (AVE8112) is an orally active PDE4 inhibitor. Tilivapram can regulate neurophysiological activities and improve cognitive and memory impairments. Tilivapram can be used in the research of various neuropsychiatric disorders such as schizophrenia and Parkinson's disease[1].
Product Specifications
CAS Number
[166741-91-9]
Product Name Alternative
AVE8112
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Purity
99.96
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC1=C(NC(C2=NC=C(OC)C(OCC3CC3)=C2)=O)C(Cl)=C[N+]([O-])=C1
Molecular Formula
C16H15Cl2N3O4
Molecular Weight
384.21
References & Citations
[1]Amit Etkin, et al. Treatment of neuropsychiatric disorders with tilivapram. WO2025080415A1. 2025-04-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
Available Sizes
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