SCH 47896
SCH 47896 is a phenolic derivative of SCH39370 (HY-139803), a potent specific inhibitor of metalloendopeptidase (NEP) . SCH 47896 can be used for the research of cardiovascular disease, such as hypertension[1].
Product Specifications
CAS Number
[142621-29-2]
UNSPSC
12352005
Target
Drug Derivative; Neprilysin
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(O)C[C@H](O)NC([C@H](CC1=CC=CC=C1)N[C@H](C(O)=O)CCC2=CC=C(O)C=C2)=O
Molecular Formula
C22H26N2O7
Molecular Weight
430.45
References & Citations
[1]Kanazawa M, et al. Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor. J Pharmacol Exp Ther. 1992 Jun;261 (3) :1231-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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