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NHS-Modified MMAF (TFA)

NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) [1].

Product Specifications

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Purity

96.03

Smiles

O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45.OC(C(F)(F)F)=O

Molecular Formula

C57H87F3N8O14

Molecular Weight

1165.34

References & Citations

[1]Lerchen HG, et, al. Novel binder-drug conjugates (adcs) and their use. WO2012143499A2.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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