Thailanstatin B
Thailanstatin B is a potent pre-mRNA splicing inhibitor (IC50=6.18 μM) . Thailanstatin B shows antiproliferative activity[1].
Product Specifications
CAS Number
[1426953-23-2]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2[C@H]([C@@](O)(C[C@H](O2)CC(O)=O)CCl)O
Molecular Formula
C28H42ClNO9
Molecular Weight
572.09
References & Citations
[1]Liu X, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013;76 (4) :685-693.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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