BLT-4

BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) . BLT-4 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. [1].

Product Specifications

CAS Number

[251917-79-0]

UNSPSC

12352005

Hazard Statement

H410

Target

LXR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Smiles

O=C(NC1=CC=C2C=CC=CC2=C1)NC3=CC=CC=C3OC

Molecular Formula

C18H16N2O2

Molecular Weight

292.33

Precautions

P273-P391-P501

References & Citations

[1]Nieland TJ, et al. Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res. 2004;45 (7) :1256-1265.