SM1-71-R
SM1-71-R is a reversible analog o SM1-71 (HY-136848) . SM1-71-R lacks the acrylamide warhead and therefore cannot form a covalent bond with the kinase. SM1-71-R can be used as a control compound for SM1-71[1].
Product Specifications
CAS Number
[2088180-03-2]
UNSPSC
12352005
Target
Akt
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Purity
98.70
Smiles
O=C(CC)NC1=C(C=CC=C1)NC2=NC(NC3=CC=C(N(CC4)CCN4C)C=C3)=NC=C2Cl
Molecular Formula
C24H28ClN7O
Molecular Weight
465.98
References & Citations
[1]Rao S, et al. A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers. J Biol Chem. 2019 May 24;294 (21) :8664-8673.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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