Anhydro abiraterone

Anhydro abiraterone is a degradation product of Abiraterone acetate (HY-75054) . Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity[1][2].

Product Specifications

CAS Number

[154229-20-6]

UNSPSC

12352005

Hazard Statement

H361-H373-H410

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

C[C@@]1(C(C2=CN=CC=C2)=CC3)[C@]3([H])[C@@](CC=C4[C@@]5(CCC=C4)C)([H])[C@]5([H])CC1

Molecular Formula

C24H29N

Molecular Weight

331.49

Precautions

P260-P273-P280-P391-P405-P501

References & Citations

[1]Deepak Krishna Mhaske, et al. The first RP-UHPLC method for simultaneous quantification of abiraterone acetate, its four degradants, and six specified process impurities and correct identification of all analytes based on molecular weight. J Pharm Biomed Anal. 2023 Sep 20:234:115568. |[2]Stein MN, et al. Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer. Asian J Androl. 2014 May-Jun;16 (3) :387-400.