Carbuterol
Carbuterol (SKF 40383-A) is a selective β2-adrenergic receptor agonist that primarily targets bronchial smooth muscle, exhibiting significant bronchodilatory and anti-allergic activity. Carbuterol can directly inhibit the immunologically induced release of histamine and slow-reacting substance of anaphylaxis (SRS-A), thereby alleviating allergic responses. Carbuterol exerts mild β1-mediated cardiac stimulation and is applicable to studies related to respiratory and immune-related diseases such as asthma and allergic disorders[1].
Product Specifications
CAS Number
[34866-47-2]
Product Name Alternative
SKF 40383-A
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(N)NC1=CC(C(O)CNC(C)(C)C)=CC=C1O
Molecular Formula
C13H21N3O3
Molecular Weight
267.32
References & Citations
[1]Colella DF, et al. Characterization of the adrenergic activity of carbuterol (SK&F 40383-A) . Eur J Pharmacol. 1977 Dec 1;46 (3) :229-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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