Lemuteporfin

Lemuteporfin (QLT-0074) is a benzoporphyrin derivative, diethylene glycol functionalized chlorin-type photosensitizer. Lemuteporfin rapidly sensitizes cells to photodynamic therapy. Lemuteporfin has anticancer activity against acute lymphoblastic leukemia[1].

Product Specifications

CAS Number

[215808-49-4]

Product Name Alternative

QLT-0074; DRM-05; EA 6

UNSPSC

12352005

Target

Drug Derivative; Photosensitizer

Related Pathways

Apoptosis; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(OC)C1=CC=C2C(C1C(OC)=O)(C)/C3=C/C4=N/C(C(CCC(OCCO)=O)=C4C)=C\C(N5)=C(CCC(OCCO)=O)C(C)=C5/C=C6C(C=C)=C(C)C(/C=C2\N3)=N/6

Molecular Formula

C44H48N4O10

Molecular Weight

792.87

References & Citations

[1]Boch R, et al. Cellular and antitumor activity of a new diethylene glycol benzoporphyrin derivative (lemuteporfin) . Photochem Photobiol. 2006 Jan-Feb;82 (1) :219-24.