Ro4368554
Ro4368554 is a brain-penetrant and selective 5-HT6 antagonist that reverses memory deficits induced by scopolamine and tryptophan depletion. Ro4368554 can be utilized in research related to memory deficits[1].
Product Specifications
CAS Number
[478082-99-4]
UNSPSC
12352005
Hazard Statement
H302
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=S(C1=CNC2=C1C=CC=C2N3CCN(C)CC3)(C4=CC=CC=C4)=O
Molecular Formula
C19H21N3O2S
Molecular Weight
355.45
Precautions
P264-P270-P330-P501
References & Citations
[1]Lieben CK, et al. The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat. Neuropsychopharmacology. 2005 Dec;30 (12) :2169-79.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor; MUC2
Curated Selection
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