Aldi-2
Aldi-2 is a potent and specific covalent inhibitor of aldehyde dehydrogenases (ALDHs) with IC50s of 2.5, 6.4 and 1.9 μM against ALDH1A1, ALDH2 and ALDH3A1, respectively. Aldi-2 can be utilized in cancer research[1].
Product Specifications
CAS Number
[499997-25-0]
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease
Smiles
O=C(C1=CC=C(OC)C(F)=C1)CCN(C)C
Molecular Formula
C12H16FNO2
Molecular Weight
225.26
References & Citations
[1]Khanna M, et al. Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases. J Biol Chem. 2011 Dec 16;286 (50) :43486-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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