DHNA
DHNA (KIS20) is a PDH kinase 4 (PDK4) inhibitor with an IC50 of 18 μM. DHNA can be used for the study of heart failure[1].
Product Specifications
CAS Number
[117255-85-3]
Product Name Alternative
1,4-Dihydroxy-6-naphthoic acid
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
PDHK
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Concentration
10mM
Purity
99.65
Solubility
DMSO : 100 mg/mL
Smiles
O=C(C1=CC=C2C(O)=CC=C(O)C2=C1)O
Molecular Formula
C11H8O4
Molecular Weight
204.18
Precautions
H302, H312, H332
References & Citations
[1]Katsuhito Fujiu, et al. A therapeutic and prophylactic agent for heart failure containing a novel PDK4 inhibitor as an active ingredient. JP2015160831A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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