(2E) -TCO-PNB ester
(2E) -TCO-PNB ester is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. (2E) -TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
Product Specifications
CAS Number
[1580501-97-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)OC2/C=C/CCCCC2
Molecular Formula
C15H17NO5
Molecular Weight
291.30
Precautions
H315, H319, H335
References & Citations
[1]Natasha Bidesi, et al. Synthesis and radiolabeling of a polar [125 I]I-1,2,4,5-tetrazine. J Labelled Comp Radiopharm. 2023 Jan;66 (1) :22-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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