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TH301

TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period[1].

Product Specifications

CAS Number

[450338-32-6]

UNSPSC

12352005

Target

Cryptochrome; Drug Derivative

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Smiles

O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NC3=C4C(CS(C4)(=O)=O)=NN3C5=CC=C(OC)C=C5

Molecular Formula

C24H24ClN3O4S

Molecular Weight

485.98

References & Citations

[1]Miller S, et al. Isoform-selective regulation of mammalian cryptochromes. Nat Chem Biol. 2020 Jun;16 (6) :676-685.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CRY2

Curated Selection

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