JMV 3008
JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity[1].
Product Specifications
CAS Number
[925239-09-4]
UNSPSC
12352005
Target
GHSR
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Smiles
O=C([C@H]1NCCC1)N[C@@H](C2=NN=C(CCC3=CNC4=C3C=CC=C4)N2CC5=CC=C(OC)C=C5OC)CC6=CNC7=C6C=CC=C7
Molecular Formula
C36H39N7O3
Molecular Weight
617.74
References & Citations
[1]Hanrahan P, et al. Substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity. Bioorg Med Chem Lett. 2012 Mar 15;22 (6) :2271-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GHSR1a
Curated Selection
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