(R) -FTY720-OMe
(R) -FTY720-OMe is a selective SphK2 inhibitor with an IC50 of 16.5 μM. (R) -FTY720-OMe can be used for cancer, fibrosis, and Alzheimer’s and sickle cell diseases research[1].
Product Specifications
CAS Number
[1382486-90-9]
UNSPSC
12352005
Target
SphK
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
COC[C@@](CO)(N)CCC1=CC=C(C=C1)CCCCCCCC
Molecular Formula
C20H35NO2
Molecular Weight
321.50
References & Citations
[1]Congdon MD, et al. Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors. ACS Med Chem Lett. 2016 Feb 2;7 (3) :229-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SphK2
Curated Selection
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