Imetelstat
Imetelstat is an 13‐mer oligonucleotide that binds with high affinity to the template region of the RNA component of human telomerase and acts as a competitive inhibitor of human telomerase enzymatic activity[1].
Product Specifications
CAS Number
[868169-64-6]
Product Name Alternative
GRN163L
UNSPSC
12352208
Target
Telomerase
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.43
Smiles
[Imetelstat]
Molecular Formula
C148H211N68O53P13S13
Molecular Weight
4610.00
References & Citations
[1]Ashley L Lennox, et al. Imetelstat, a novel, first-in-class telomerase inhibitor: Mechanism of action, clinical, and translational science. Review Clin Transl Sci. 2024 Nov;17 (11) :e70076.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
Launched
Available Sizes
Curated Selection
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