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(±) -WB 4101

(±) -WB 4101 is a highly selective α1-adrenergic receptor antagonist. (±) -WB 4101 blocks norepinephrine-induced vascular smooth muscle contraction to exert antihypertensive and benign prostatic hyperplasia (BPH) -relieving effects. (±) -WB 4101 is promising for research of hypertension and BPH[1].

Product Specifications

CAS Number

[613-67-2]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

COC1=C(OCCNCC2OC3=CC=CC=C3OC2)C(OC)=CC=C1

Molecular Formula

C19H23NO5

Molecular Weight

345.39

References & Citations

[1]Orav E, et al. Arginine vasopressin activates serotonergic neurons in the dorsal raphe nucleus during neonatal development in vitro and in vivo. Neuropharmacology. 2024 Nov 1;258:110068.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Curated Selection

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