L-685487

L-685487 is a 13-desmethyl derivative of FK506 (HY-13756) . L-685487 is promising for research of immunomodulators[1].

Product Specifications

CAS Number

[132055-38-0]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@@](O2)([H])[C@H](O)[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O

Molecular Formula

C42H67NO12

Molecular Weight

777.98

References & Citations

[1]Chen TS, et al. Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. J Antibiot (Tokyo) . 1992 Apr;45 (4) :577-80.