Lonomycin C

Lonomycin C is a demethyl derivative of Lonomycin A or Lonomycin B. Lonomycin C can be concluded to be a new member of polyether antibiotic family. Lonomycin C is active against Gram-positive bacteria but inactive against Gram-negative bacteria and fungi. Lonomycin C is slightly less active than Lonomycin A in antimicrobial activities[1].

Product Specifications

CAS Number

[68537-50-8]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(O)C[C@]1(O)[C@H](C)[C@@H](OC)[C@@H](C)[C@@H]([C@@H]([C@H]([C@H](C)[C@@H](OC)C2)O[C@]32CC[C@]([C@H]4CC[C@]([C@@H]5O[C@@H]([C@@H]6[C@@H](C)[C@H](OC)[C@@H](C)[C@@](C)(O)O6)[C@H](OC)[C@@H]5C)(C)O4)(C)O3)C)O1

Molecular Formula

C43H74O14

Molecular Weight

815.04

References & Citations

[1]Mizutani T, et al. Lonomycins B and C, two new components of polyether antibiotics. Fermentation, isolation and characterization. J Antibiot (Tokyo) . 1980 Nov;33 (11) :1224-30.