ST-162
ST-162 is a MAPK/PI3K dual antagonist. ST-162 exhibits antitumor activity and can increase the efficacy of immune checkpoint blockers. ST-162 can be used for the research of cancer, such as melanoma[1].
Product Specifications
CAS Number
[1883817-83-1]
UNSPSC
12352005
Target
P38 MAPK; PI3K
Related Pathways
MAPK/ERK Pathway; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(NOCCOCCOCCOCCN1CCN(C2=NC(N3C4=CC=CC=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)CC1)C6=CC=C(F)C(F)=C6NC7=CC=C(I)C=C7F
Molecular Formula
C40H44F5IN10O6
Molecular Weight
982.74
References & Citations
[1]Galbán S, et al. A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis. Mol Cancer Ther. 2017 Nov;16 (11) :2340-2350.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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