MRL-1237

MRL-1237 is an inhibitor of the replication of several enteroviruses targeting the non-structural protein 2C of the virus. MRL-1237 shows effective inhibition against poliovirus and various other enteroviruses. MRL-1237 does not inhibit the NTPase (ATPase) activity of 2C protein. MRL-1237 can be used for the research of infection[1].

Product Specifications

CAS Number

[276704-21-3]

UNSPSC

12352005

Target

Enterovirus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

N=C1C=CN(CC2=NC3=CC=CC=C3N2C4=CC=C(F)C=C4)C=C1.Cl

Molecular Formula

C19H16ClFN4

Molecular Weight

354.81

References & Citations

[1]De Palma AM, et al. The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C. J Virol. 2008 May;82 (10) :4720-30.