CCG 102487
CCG-102487 is a streptokinase (SK) inhibitor. CCG-102487 impairs bacterial exploitation of host fibrinolysis and enhances neutrophil phagocytosis. CCG-102487 is promising for research of streptococcal infections (e.g., pharyngitis, necrotizing fasciitis) [1].
Product Specifications
CAS Number
[353787-50-5]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1N(CC=C)C(SCC2=CC=CC=C2)=NC3=C1C4(CCCCC4)CC5=CC=CC=C53
Molecular Formula
C27H28N2OS
Molecular Weight
428.59
References & Citations
[1]Sun H, et al. Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. Proc Natl Acad Sci U S A. 2012 Feb 28;109 (9) :3469-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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