AZD-9819
AZD-9819 is a neutrophil elastase (HNE) inhibitor. AZD-9819 can be used to study chronic obstructive pulmonary disease[1].
Product Specifications
CAS Number
[956907-23-6]
UNSPSC
12352005
Target
Elastase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=NC(C2=CC=NN2C3=CC=C(C#N)C=C3)=C(C)N(C4=CC=CC(C(F)(F)F)=C4)C1=O)NCC
Molecular Formula
C25H19F3N6O2
Molecular Weight
492.45
References & Citations
[1]Gu C, et al. Lipid Peroxide-Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples. Drug Metab Dispos. 2015 Oct;43 (10) :1441-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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