SCH 350581

SCH 350581 (AD-101) is a CCR5 antagonist. SCH 350581 inhibits HIV-1 replication, viral entry into cells, and the binding of gp120 to cell lines in primary lymphocytes[1].

Product Specifications

CAS Number

[306293-36-7]

Product Name Alternative

AD-101

UNSPSC

12352005

Target

CCR

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C(C1=C(C)C=CN=C1C)N2CCC(N3C[C@H](C)N([C@H](C4=CC=C(C(F)(F)F)C=C4)C)CC3)(C)CC2

Molecular Formula

C28H37F3N4O

Molecular Weight

502.61

References & Citations

[1]Tsamis F, et al. Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry. J Virol. 2003 May;77 (9) :5201-8.