MK-0916
MK-0916 is a HSD1 inhibitor. MK-0916 produces mechanism-based activation of the hypothalamic-pituitary-adrenal axis. MK-0916 can be used in the research of type 2 diabetes and metabolic syndromes[1].
Product Specifications
CAS Number
[633317-53-0]
UNSPSC
12352005
Target
11β-HSD
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
F[C@@H]1C[C@](C2=NN=C(C3CC3)N2C4CC4)(C5=CC=C(C=C5)Cl)C1
Molecular Formula
C18H19ClFN3
Molecular Weight
331.81
References & Citations
[1]Feig PU, et al. Effects of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome. Diabetes Obes Metab. 2011 Jun;13 (6) :498-504.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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