(S, S) -D211
(S, S) -D211 is a stereoisomer of D211. (S, S) -D211 belongs to PBD dimer family with DNA damage activity. (S, S) -D211 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1971075-99-6]
UNSPSC
12352005
Target
ADC Payload; DNA/RNA Synthesis
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1N2[C@@](C=NC3=CC(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(CC7=CC=CC=C7C6)C5=O)=C4)OC)=C(OC)C=C31)([H])CC8=CC=CC=C8C2
Molecular Formula
C39H36N4O6
Molecular Weight
656.73
References & Citations
[1]Smith SW, et al. Design and Synthesis of Isoquinolidinobenzodiazepine Dimers, a Novel Class of Antibody-Drug Conjugate Payload. ACS Med Chem Lett. 2017 Dec 6;9 (1) :56-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1417490-01 0.02 mg (E-Coli)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details 
MBS1417490-02 0.02 mg (Yeast)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details 
MBS1417490-03 0.1 mg (E-Coli)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details MBS1417490-04 0.1 mg (Yeast)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details MBS1417490-05 0.02 mg (Baculovirus)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details MBS1417490-06 0.02 mg (Mammalian-Cell)
Recombinant Staphylococcus aureus Probable siderophore biosynthesis protein SbnA (sbnA)
Ask
View Details