TAK-100
TAK-100 is a selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor with an IC50 of 5.3 nM. TAK-100 hass little or no inhibitory effects on other dipeptidyl peptidase members. TAK-100 can be used for the study of diabetes[1].
Product Specifications
CAS Number
[907609-33-0]
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(O)CC1=C(C2=CC=C(C)C=C2)C(CN)=C(CC(C)(C)C)N=C1CC
Molecular Formula
C22H30N2O2
Molecular Weight
354.49
References & Citations
[1]Miyamoto Y, et al.. Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor. J Med Chem. 2011 Feb 10;54 (3) :831-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
DPP-4
Curated Selection
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