MK-0448
MK-0448 is a specific Kv1.5 inhibitor used in the research of atrial fibrillation[1].
Product Specifications
CAS Number
[875562-81-5]
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Purity
99.79
Smiles
CS(=O)(NC1=NC([C@H](C2=CC=C(F)C=C2)C(C3=CC=CN=C3)C4=CC=CN=C4)=CC=C1)=O
Molecular Formula
C24H21FN4O2S
Molecular Weight
448.51
References & Citations
[1]Pavri BB, et al. MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans. Circ Arrhythm Electrophysiol. 2012 Dec;5 (6) :1193-201.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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