PH-46A
PH-46A is an indane dimer with anti-inflammatory activity. PH-46A can reduced histological damage and serum amyloid A (SAA) levels in colitis mice[1].
Product Specifications
CAS Number
[1380445-04-4]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(O)C1=CC=C(C[C@]2(C(C3)=CC4=C3C=CC=C4)[C@H](O)C5=C(C=CC=C5)C2)C=C1.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC
Molecular Formula
C33H39NO8
Molecular Weight
577.66
References & Citations
[1]Frankish N, et al. 6- (methylamino) hexane-1,2,3,4,5-pentanol 4- (((1S,2S) -1-hydroxy-2,3-dihydro-1H,1'H-[2,2-biinden]-2-yl) methyl) benzoate (PH46A) : a novel small molecule with efficacy in murine models of colitis. J Med Chem. 2012 Jun 14;55 (11) :5497-505.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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