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(S) -TROX-1

(S) -TROX-1 is the S-enantiomer of TROX-1 (HY-120751) . TROX-1 is a state-dependent N-type calcium channel (CaV2.2) inhibitor[1].

Product Specifications

CAS Number

[2751591-42-9]

UNSPSC

12352005

Target

Drug Isomer

Related Pathways

Others

Field of Research

Neurological Disease

Purity

99.52

Smiles

O=C1N(C2=C([C@@]1(CC3=CN=CN=C3)C)C=C(C=C2)C4=CC=C(C(Cl)=C4)F)C5=NNC=N5

Molecular Formula

C22H16ClFN6O

Molecular Weight

434.85

References & Citations

[1]Swensen AM, et al. Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Ca (V) 2 calcium channels. Mol Pharmacol. 2012 Mar;81 (3) :488-97.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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