DCAI
DCAI is Ras protein binder. DCAI can inhibit the Ras activation and nucleotide exchange mediated by SOS. DCAI can be used for the research of cancer associated with Ras mutations [1].
Product Specifications
CAS Number
[299165-92-7]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Smiles
CC(NC1=C2C(Cl)=CC(Cl)=C1)=C2CCN
Molecular Formula
C11H12Cl2N2
Molecular Weight
243.13
Precautions
P261-P280-P302+P352
References & Citations
[1]Maurer T, et al. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Apr 3;109 (14) :5299-304.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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