Tetranor-PGAM

Tetranor-PGAM is a tetranor-prostaglandin A metabolite. Tetranor-PGAM is a dehydration product of tetranor-PGEM (HY-114988) . Tetranor-PGAM can be measured as a surrogate for tetranor-PGEM levels in urine[1][2].

Product Specifications

CAS Number

[52510-53-9]

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Solubility

10 mM in DMSO

Smiles

OC(CC[C@@H]1[C@H](C=CC1=O)CCC(CCCCC(O)=O)=O)=O

Molecular Formula

C16H22O6

Molecular Weight

310.34

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Gregory W. Endres, et al. Methods for manufacturing tetranor-prostaglandin d, j, e, a and f metabolites. Patent, WO2011159740A2.|[2]Neale JR, et al. Liquid chromatography-tandem mass spectrometric quantification of the dehydration product of tetranor PGE-M, the major urinary metabolite of prostaglandin E (2) in human urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Aug 1;871 (1) :72-7.