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Jingsongling

Jingsongling is a Xylazine analog and anesthetic agent. Jingsongling causes bradycardia and hypertension by mediating α2-adrenoceptors. Jingsongling inhibits canine gastric motility through mediation of α1 and α2 adrenergic receptors[1][2][3].

Product Specifications

CAS Number

[25332-05-2]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Adrenergic Receptor; Drug Derivative

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

CC1=C(NC2=NCCS2)C(C)=CC=C1

Molecular Formula

C11H14N2S

Molecular Weight

206.31

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Hsu WH, et al. The effects of jingsongling, a xylazine analog, on mean arterial blood pressure and heart rate in dogs--influences of yohimbine, tolazoline, prazosin, and atropine. J Vet Pharmacol Ther. 1989 Sep;12 (3) :283-8. |[2]Lin DeGui L D G, et al. Studies on effect of Jingsongling on canine gastric peristalsis[J]. 2001.|[3]Guo LQ, et al. [Studies on biotransformation of jing song ling, a new anesthetic]. Yao Xue Xue Bao. 1990;25 (2) :95-100. Chinese.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Curated Selection

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