CGS 24012
CGS 24012 (DPMA) is a selective adenosine A2 agonist. CGS 24012 produces significant increases in cardiac output. CGS 24012 reduces renal vascular resistance to the greatest extent and produces a concomitant significant increase in renal blood flow. CGS 24012 can be used in the research of hypertension[1].
Product Specifications
CAS Number
[120442-40-2]
Product Name Alternative
DPMA; PD 125944
UNSPSC
12352005
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
N(CC(C1=CC(OC)=CC(OC)=C1)C2=C(C)C=CC=C2)C3=C4C(N(C=N4)[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)=NC=N3
Molecular Formula
C27H31N5O6
Molecular Weight
521.57
References & Citations
[1]Webb RL, et al. Cardiovascular effects of adenosine A2 agonists in the conscious spontaneously hypertensive rat: a comparative study of three structurally distinct ligands. J Pharmacol Exp Ther. 1991 Dec;259 (3) :1203-12.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118229/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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