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FE-999024

FE-999024 (CH-2856) is a specific tissue kallikrein inhibitor. FE-999024 can inhibit cancer cells invasion with a maximum of 39%. FE-999024 can reduce eosinophilia in a model of allergic inflammation. FE-999024 can be used for the researches of cancer, inflammation and immunology[1][2].

Product Specifications

CAS Number

[168825-65-8]

Product Name Alternative

CH-2856

UNSPSC

12352005

Target

Kallikrein

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(N)[C@H](CC1=C2C=CC=CC2=CC=C1)N(C([C@@H](CC3=CC=C(Cl)C=C3)N)=O)CCCNC(N)=N

Molecular Formula

C26H31ClN6O2

Molecular Weight

495.02

References & Citations

[1]Wolf WC, et al. A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. Am J Pathol. 2001 Nov;159 (5) :1797-805.|[2]Evans DM, et al. Synthetic inhibitors of human tissue kallikrein. Immunopharmacology. 1996 May;32 (1-3) :117-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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