XV459
XV459 is an orally active platelet GPIIb/IIIa receptor antagonist. XV459 blocks all agonist induced platelet aggregation by binding to platelet GPIIb/IIIa receptors. XV459 can significantly prolong occlusion time, reduce thrombus weight, and maintain blood flow. XV459 can be used for anti thrombotic research[1].
Product Specifications
CAS Number
[170902-52-0]
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Smiles
O=C([C@@H](NC(OCCCC)=O)CNC(C[C@H]1CC(C2=CC=C(C=C2)C(N)=N)=NO1)=O)O
Molecular Formula
C20H27N5O6
Molecular Weight
433.46
References & Citations
[1]Mousa SA, et al. Intravenous and oral antithrombotic efficacy of the novel platelet GPIIb/IIIa antagonist roxifiban (DMP754) and its free acid form, XV459. Arterioscler Thromb Vasc Biol. 1999 Oct;19 (10) :2535-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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