AL-1
AL-1 is a potent O2- generation inhibitor (IC50 = 7.6 μM) through the inhibition of leukocytic NADPH oxidase. AL-1 inhibits 12-O-Tetradecanoylphorbol-13-acetate (TPA) -induced H2O2 production. AL-1 reduces tumor incidence in ICR mouse skin. AL-1 can be used for research on oxidative stress-related diseases including cancer[1].
Product Specifications
CAS Number
[126455-04-7]
UNSPSC
12352005
Target
NADPH Oxidase; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Smiles
CC#CC#C/C=C1[C@]2([H])[C@](O2)([H])[C@@]3(CC[C@@H](CO3)OC(CC(C)C)=O)O\1
Molecular Formula
C19H22O5
Molecular Weight
330.37
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114809/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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