SR-4559
SR-4559 (Compound 4) is a α/β hydrolase domain-containing protein 5 (ABHD5) ligand. SR-4559 activates adipose triglyceride lipase (ATGL) and stimulates lipolysis by inhibiting ABHD5-PLIN interactions in adipocytes and muscle cells. SR-4559 can be used for metabolic diseases like Chanarin Dorfman syndrome research[1]
Product Specifications
CAS Number
[847939-23-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
ATGL
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Purity
98.81
Smiles
O=S(C1=CC=C(OCCO2)C2=C1)(N3CCN(C(CC4=COC5=C4C=CC(C)=C5)=O)CC3)=O
Molecular Formula
C23H24N2O6S
Molecular Weight
456.51
Precautions
H315, H319, H335
References & Citations
[1]Lum KM, et al. Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12 (10) :2671-2681.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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