MS2734
MS2734 is a inhibitor of nicotinamide N-methyltransferase (NNMT) . MS2734 potently inhibits the methyltransferase activity of human NNMT (hNNMT) with an IC50 value of 14 μM. MS2734 can be used for the study of obesity, diabetes, Parkinson's disease, and various cancers with high NNMT expression[1].
Product Specifications
CAS Number
[2587612-25-5]
UNSPSC
12352005
Target
Amine N-methyltransferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Smiles
O[C@@H]1[C@H](O)[C@@H](CN(CCC[C@H](N)C(O)=O)CCC2=CC(C(N)=O)=CC=C2)O[C@H]1N3C=NC4=C(N)N=CN=C43
Molecular Formula
C24H32N8O6
Molecular Weight
528.56
References & Citations
[1]Babault N, et al. Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) . J Med Chem. 2018 Feb 22;61 (4) :1541-1551.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Lentiviral mouse F9 shRNA (UAS) - Lentiviral mouse F9 shRNA (UAS, RFP) plasmid
