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Estrone acetate

Estrone acetate (Hogival) is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density) . Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models[1].

Product Specifications

CAS Number

[901-93-9]

Product Name Alternative

Hogival; Oestrone-3-acetate; Puboestrene

UNSPSC

12352005

Hazard Statement

H301-H311-H315-H319-H331-H335-H351

Target

Estrogen Receptor/ERR

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Smiles

C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OC(C)=O)=C4)[C@@]3([H])CC1)C2=O

Molecular Formula

C20H24O3

Molecular Weight

312.40

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

References & Citations

[1]McComb DJ, et al. Enhanced responsiveness of lactotrophs in ectopic pituitaries to bromocryptine and estrone acetate. Acta Anat (Basel) . 1981;110 (2) :113-20.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111182/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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