A 56234
A 56234 is an orally active benzisoxazole diuretic. A 56234 produces dose-dependent diuresis, sodium and chloride excretion, significantly increases potassium excretion, and also slightly increases calcium, magnesium, and total protein excretion. A 56234 has shown uricosuric effects in animal studies[1]
Product Specifications
CAS Number
[90247-09-9]
UNSPSC
12352005
Target
Potassium Channel; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Smiles
O=C(C1CC2=CC3=C(ON=C3C4=CC=CC=C4F)C(Cl)=C2O1)O[K]
Molecular Formula
C16H8ClFKNO4
Molecular Weight
371.79
References & Citations
[1]Luther RR, et al. Pharmacologic effects of A-56234, a new high-ceiling diuretic. J Clin Pharmacol. 1988 Sep;28 (9) :795-803.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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