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TNK-651

TNK-651 is a non-nucleoside HIV-1 reverse transcriptase inhibitor. TNK-651 exhibits inhibitory effects on both the HIV-1 SF33 strain and the NNRTI-resistant HIV-1 A17 strain. TNK-651 can be used for the study of HIV-1 infection[1].

Product Specifications

CAS Number

[175739-42-1]

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1C(C(C)C)=C(CC2=CC=CC=C2)N(COCC3=CC=CC=C3)C(N1)=O

Molecular Formula

C22H24N2O3

Molecular Weight

364.44

References & Citations

[1]Wang X, et al. Design, synthesis, and biological evaluation of 1-[ (2-benzyloxyl/alkoxyl) methyl]-5-halo-6-aryluracils as potent HIV-1 non-nucleoside reverse transcriptase inhibitors with an improved drug resistance profile.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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