Crofelemer
Crofelemer (Provir) is an orally active antidiarrheal agent. Crofelemer acts on the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer can be used in the research of diarrheal diseases[1].
Product Specifications
CAS Number
[148465-45-6]
Product Name Alternative
Provir; SP 303
UNSPSC
12352211
Target
CFTR; Chloride Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Smiles
[Crofelemer]
References & Citations
[1]Cottreau J, et al. Crofelemer for the treatment of secretory diarrhea. Expert Rev Gastroenterol Hepatol. 2012 Feb;6 (1) :17-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
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