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PROTAC Her3-binding moiety 2

PROTAC Her3-binding moiety 2 is a Her3 inhibitor. PROTAC Her3-binding moiety 2 can be used for synthesis of PROTAC Her3 Degrader-8 (HY-153796) [1].

Product Specifications

CAS Number

[2103332-05-2]

UNSPSC

12352005

Target

EGFR; Ligands for Target Protein for PROTAC

Related Pathways

JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

C=CC(NC1=CC(C2=NN(C3CCNCC3)C4=NC=NC(N)=C42)=CC=C1OC5=CC=CC=C5)=O

Molecular Formula

C25H25N7O2

Molecular Weight

455.51

References & Citations

[1]Gray N, et al. Bifunctional molescules for her3 degradation and methods of use. WO2017117473A1. 2017-08-24.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ErbB3/HER3

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