Echinocandin B nucleus

Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B (HY-125723) deacylase. Echinocandin B nucleus serves as an intermediate for the synthesis of semi-synthetic antifungal agents[1].

Product Specifications

CAS Number

[79411-15-7]

Product Name Alternative

SL 7810 nucleus; A-30912 A nucleus

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Intermediate; Fungal

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C1N2[C@@](C(N[C@@H]([C@@H](C[C@@H](C(N[C@@](C(N3[C@](C[C@H](C3)O)([H])C(N[C@@](C(N[C@@]1([H])[C@H](O)C)=O)([H])[C@H](O)[C@H](C4=CC=C(C=C4)O)O)=O)=O)([H])[C@H](O)C)=O)N)O)O)=O)([H])[C@H]([C@H](C2)C)O

Molecular Formula

C34H51N7O15

Molecular Weight

797.81

Precautions

P264-P270-P330-P501

References & Citations

[1]Lei Shao, et al. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains. Appl Environ Microbiol. 2013 Feb;79 (4) :1126-33.|[2]Bernard J. Abbott, et al. A-30912A Nucleus. US4293482A. 1981-10-06.