CLT-28643

CLT-28643 is an integrin α5β1 inhibitor. CLT-28643 can inhibit the high expression of integrin α5β1 in the bleb at early time-points after surgery and promote wound healing process[1].

Product Specifications

CAS Number

[1153631-91-4]

UNSPSC

12352005

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Others

Smiles

CNC(C1=CC(C(NC2=CC=C(OC)C=C2)=C(C(O)=O)C=N3)=C3C=C1)=O

Molecular Formula

C19H17N3O4

Molecular Weight

351.36

References & Citations

[1]Van Bergen T, et al. Integrin α5β1 Inhibition by CLT-28643 Reduces Postoperative Wound Healing in a Mouse Model of Glaucoma Filtration Surgery. Invest Ophthalmol Vis Sci. 2016 Nov 1;57 (14) :6428-6439.