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Dinalbuphine sebacate

Dinalbuphine sebacate (Sebacoyldinalbuphine) is a prodrug of Nalbuphine (a κ receptor agonist and μ receptor partial antagonist) . Dinalbuphine sebacate releases Nalbuphine after hydrolysis, providing a pain relief effect lasting up to 7 days. Dinalbuphine sebacate can be used for moderate to severe postoperative pain[1][2].

Product Specifications

CAS Number

[311768-81-7]

Product Name Alternative

Sebacoyldinalbuphine

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC6CCC6)CC4)C=CC(OC(CCCCCCCCC(OC7=C8C9=C(C=C7)C[C@](N(CC%10CCC%10)CC%11)([H])[C@@]%12(O)[C@]9%11[C@@]([C@H](CC%12)O)([H])O8)=O)=O)=C5O[C@@]3([H])[C@@H](O)CC1

Molecular Formula

C52H68N2O10

Molecular Weight

881.10

References & Citations

[1]Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD) : National Institute of Child Health and Human Development; 2006–. Nalbuphine. 2025 Jul 15. |[2]Tang SL, et al. Breast Milk Excretion of Dinalbuphine Sebacate Injection Administered After Cesarean Section. J Clin Pharmacol. 2024 Jun;64 (6) :755-761.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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