CGP 53437
CGP 53437 is an orally active HIV-1 protease inhibitor, with a Ki of 0.2 nM. CGP 53437 delays the onset of HIV replication[1].
Product Specifications
CAS Number
[150736-68-8]
UNSPSC
12352005
Target
HIV; Virus Protease
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(N1CCOCC1)[C@@H](NC([C@H](C(C)C)NC([C@@H](C[C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC2=CC=CC=C2)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4
Molecular Formula
C42H56N4O7
Molecular Weight
728.92
References & Citations
[1]Alteri E, et al. CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity. Antimicrob Agents Chemother. 1993 Oct;37 (10) :2087-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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